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gamma-Cyclodextrin

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  • Published: 2013-08-02
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Introduction
γ-CYCLODEXTRIN
Prepared at the 53rd JECFA (1999) and published in FNP 52 Add 7 (1999), superseding specifications prepared at the 51st JECFA (1998), published in FNP 52 Add 6 (1998). ADI "not specified", established at the 53rd JECFA in 1999.
SYNONYMS gamma-cyclodextrin, gamma-CD, cyclooctaamylose, cyclomaltooctaose
DEFINITION A non-reducing cyclic saccharide consisting of eight alpha-1,4-linked Dglucopyranosyl units manufactured by the action of cyclomaltodextrin glucanotransferase (CGTase, EC 2.4.1.19) on hydrolysed starch followed by purification of the gamma -cyclodextrin. Purification is carried out using one of the following procedures: precipitation of a complex of gammacyclodextrin with a macrocyclic compound and subsequent extraction with n-decane followed by steam-stripping of the solvent; crystallization from the purified mother liquor containing gamma-cyclodextrin obtained by chromatographic methods with ion exchange or gel filtration; membrane separation methods such as ultra filtration and reverse osmosis.

Chemical names Cyclooctaamylose
C.A.S. number 17465-86-0
Chemical formula (C6H10O5)8
Formula weight 1297
Assay Not less than 98% on an anhydrous basis
DESCRIPTION Virtually odourless, white or almost white crystalline solid
FUNCTIONAL USES Carrier, flavour modifier, stabilizer
 
 
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