AOAC Official Method 935.68 Synthetic Drugs Microchemical Tests

Microchemical Tests
First Action 1935
Final Action
(See Table 962.21B [see 18.10.02].)
(a) Acetic acid.—Dilute 6mLCH3COOHto 100mLwithH2O.
(b) Ammoniacal nickel acetate solution.—Mix 1 volume 5% Ni(CH3COO)2×4H2O solution with 1 volume NH4OH (2 + 3). Use clear supernate.
(c) Ammoniacal silver nitrate solution.—See 930.40A(a) (see 18.10.01).
(d) Ammonium thiocyanate solution.—See 930.40A(c) (see 18.10.01).
(e) Barium hydroxide solution.—Saturated aqueous solution.
(f) Benzaldehyde.—USP quality.
(g) Bismuth iodide solution.—See 930.40A(d) (see 18.10.01).
(h) Bromide–bromate solution.—Dissolve 0.3 g KBrO3 and 1.2 g KBr in H2O, and dilute to 100 mL.
(i) Glycerol–alcohol mixture.—1 + 1.
(j) Gold bromide in hydrochloric acid solution.—See 930.40A(g) (see 18.10.01).
(k) Gold chloride solution.—See 930.40A(h) (see 18.10.01).
(l) Iodine-potassium iodide solution.—See 930.40A(j) (see 18.10.01).
(m) Lead acetate solution.—Dissolve 5 g Pb(CH3COO)2×3H2O in H2O and dilute to 100 mL.
(n) Lead triethanolamine solution.—Add 1 mL triethanolamine (technical 90% is satisfactory) to solution of 1 g Pb(CH3COO)2×3H2O
in 20 mL H2O. Slight turbidity does not interfere.
(o) Magnesia mixture.—Dissolve 5.5 g MgCl2×6H2O and 14.0 g NH4Cl in H2O. Add 13.05 mL NH4OH and dilute to 100 mL with H2O.